Job Description

The Global Program Clinical Lead, Oncology (Solid Tumours) provides end-to-end medical and clinical leadership for global early development programs across solid tumour indications. This role defines the vision and strategic direction of assigned assets, ensuring a scientifically robust, medically sound development strategy from preclinical stages through early clinical development and transition to late-stage programs.

The position is accountable for shaping and executing global clinical strategy, with full decision-making authority for early development programs. It drives cross-functional alignment across research, translational science, regulatory, and clinical operations, while maximizing asset value through target product and value profile development and integration of precision medicine approaches.

Key Responsibilities

• Serve as the global clinical lead for early-stage oncology programs, providing strategic medical input into program design, execution, and go/no-go decisions.
• Define and implement clinical development strategies from preclinical evaluation through Phase I/II trials.
• Guide preclinical asset development to enable informed decision-making and seamless transition into clinical studies.
• Collaborate with translational research teams to integrate biomarkers, scientific insights, and precision medicine strategies into clinical plans.
• Oversee study design, protocol development, medical monitoring, and benefit–risk assessments to ensure high-quality execution and patient safety.
• Lead cross-functional matrix teams, fostering a culture of ownership, innovation, and peer accountability.
• Support pipeline expansion by incorporating novel assets through internal and external innovation efforts.
• Engage with external collaborators, academic partners, key opinion leaders, and regulatory authorities to inform clinical strategy.

Requirements

• Medical Degree (M.D.) with board certification in Oncology, Hematology, or a related subspecialty.
• Minimum of 5 years of direct patient care experience in oncology/hematology.
• 5+ years of pharmaceutical or biotech industry experience, including at least 2 years in early drug development.
• Strong understanding of oncology drug development, including small molecules, biologics, and novel modalities.
• Demonstrated ability to design and lead early-phase clinical trials.
• Experience interacting with regulatory authorities (FDA, EMA, etc.) and external collaborators.
• Exceptional leadership and cross-functional collaboration skills, with a track record of driving strategic impact and fostering innovation.

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